IBI Scientific
SMART-Cell Platform
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Expected Launch: Q2 2026
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Partner: IBI Scientific
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Vessel: Flow Cell
Product Overview
The SMART-Cell Platform provides users with real-time, continuous cell growth data that users can track from their phone or desktop. The platform consists of a flow cell with sterile tubing and connectors to interface with fermenters and bioreactors, a reader that includes a peristaltic pump, software to monitor cell growth, and the option to use our remote dashboard. To operate, connect the sterile tubing to an effluent or recycling stream on a fermenter or bioreactor and clip the flow cell into the reader. The reader pump pulls liquid from the reactor and assesses growth in the reactor through changes in the sensor signal (Skroot Growth Index, SGI). The growth phases are easily observed and specific points of induction, harvest, or feed can be pushed to the operator.
Product Highlights:
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Modular Approach: Can be applied to any reactor that accepts a sterile fluid line.
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No Manual Sampling: Eliminates the need for manual sampling for the entire run.
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Continuous Data: Provides full growth trends, not just sampled snapshots.
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Data From Anywhere: Monitor your cell culture straight from you phone.
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Reader Compliance: FCC, UL, REACH, RoHS, CE (pending).
SMART-Cell:
SMART sensors are integrated into the IBI flow cell during production and undergo gamma irradiation for sterilization.
The SMART sensor leverages a selective transduction membrane that softens when it is exposed to metabolites that are secreted during cell growth. As the transduction membrane softens the sensor response changes. Read more in our most recent publication.
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Software and Pump Integration:
Users control the reader with a touchscreen to provide simple lab based use (no mouse or keyboard). The interface allows the user to turn the pump on and off and to prime and clear the line. Data is reported on a display screen over the course of a run.
The continuous data is displayed locally. The reader can also transfer the growth information to a secure AWS dashboard. This can be viewed on mobile devices and desktops to track currently running flow cells and completed runs. This allows an unprecedented level of oversight on production timing and scheduling allowing for increased scale and efficiencies.
SMART-Cell Reader:
The SMART-Cell Reader includes a computational unit, touch interface, peristaltic pump, and ports to download completed reports and raw data with a USB drive. The reader is Wi-Fi capable to push information to the cloud. The pump is pre-calibrated with the supplied tubing to provide a simple, plug and play experience for the operator.
